the effects of water pipe smoking on hematological parameters in rats.

نویسندگان

ebrahim miri-moghaddam genetics of non-communicable disease research centre, zahedan university of medical sciences, zahedan, iran ; department of genetics, zahedan university of medical sciences, zahedan, iran.

ramazan mirzaei health promotion research center, faculty of health, zahedan university of medical sciences, zahedan, iran.

mohammad-reza arab depth of anatomical sciences, faculty of medicine, zahedan university of medical sciences, zahedan, iran.

samaneh kaikha students research center, zahedan university of medical sciences, zahedan, iran.

چکیده

objectives: this study aimed to investigate the effect of water-pipe (wp) smoking on hematological parameters of wistar rats. methods: thirty-five young male rats (200-250 g) were randomly assigned to five groups (n=7). the control group was exposed to room air and the experimental groups were exposed to wp smoking, using a special apparatus designed to have the ability to keep the rats for 40 minutes every day for 4, 8, 12 and 12 weeks; moreover, one of the two groups of 12 weeks of wp exposer had four following weeks of rest. blood samples were collected to evaluate red blood cell count, hemoglobin, hematocrit, white blood cell and platelet counts. results: the results showed that rbc count, hb and hct parameters were significantly higher in wp smoking rats than the control group (p< 0.001). we found that wbc counts insignificantly increased (p < 0.39) but plt counts insignificantly decreased (p < 0.13) in wp smoking rats compared with control group. conclusion: the findings may help to raise awareness of tobacco smokers about the potential toxicities of wp; likewise, the results can be used by physicians and public health officials in tobacco prevention programs.

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The Effects of Water Pipe Smoking on Hematological Parameters in Rats

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عنوان ژورنال:
international journal of hematology-oncology and stem cell research

جلد ۸، شماره ۳، صفحات ۳۷-۴۳

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